FSU vs. Louisville Betting Preview: Noles Without Key Player, Cards Now -1

Gambling911.com has your FSU vs. Louisville betting preview.  The line on this game had come down a point from Seminoles -2 but was at Louisville -1 just minutes before game time just about everywhere.  LIVE IN-PLAY WAGERING is available on this game.  (What is live in-play wagering?)

Number 2-ranked FSU (7-1 odds to win the Championship) has dominated their H2H matchups vs number 10-ranked Louisville (25-1 odds to win the Championship), going 14-2-0 all-time.  They have covered the spread in the most recent two meetings the past two seasons.

Florida State is an impressive 22-8 Against The Spread when the line is +3 to -3 and 7-2 ATS as a road favorite of 3 points or less.

The Cardinals are 5-1 ATS when the line is +3 to -3.

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Both teams have played well Against The Spread of late with the Seminoles 6-1 ATS in their last 7 games overall and 4-0 ATS in their last four overall.

There is a significant injury on the ‘Noles squad with preseason All-American sophomore safety Derwin James suffering a cartilage tear in his left knee.  He could be sidelined for up to 10 weeks.

This could provide Louisville with a significant edge coming into one of the most critical games of Week 3.

"They've been to the championship game. They've got a ring on their finger," Cardinals coach Bobby Petrino said of the 'Noles. "We knew that if we were going to make a run in this conference or run to get to the goal that we want, that we had to find a way to beat them, so we are looking forward to the matchup."

The Seminoles and Cardinals clash at noon ET Saturday in Louisville's Papa John's Cardinal Stadium on ABC.

- Ean Lamb, Gambling911,com