Louisville vs. Duke Betting Preview

Written by :

Guest

Published on :

15 March, 2025

The Louisville vs. Duke game featured a line of -6 Duke. Action was balanced.

No. 1 Duke squares off against No. 13 Louisville in the ACC Championship.

The Blue Devils are 21-1 against ACC opponents and 8-2 in non-conference play. Duke has a 1-1 record in games decided by less than 4 points.

The Cardinals are 20-2 in ACC play. Louisville is third in the ACC with 25.2 defensive rebounds per game led by J'Vonne Hadley averaging 5.2.

Duke scores 83.3 points, 14.6 more per game than the 68.7 Louisville gives up. Louisville has shot at a 45.7% rate from the field this season, 7.3 percentage points higher than the 38.4% shooting opponents of Duke have averaged.

The teams meet for the second time this season. The Blue Devils won 76-65 in the last matchup on Dec. 8. Cooper Flagg led the Blue Devils with 20 points, and Terrence Edwards led the Cardinals with 21 points.

Louisville vs. Duke Player Prop Bets

Points Scored - Rebounds - Assists

Chucky Hepburn

Louisville

(15.5) (5.5 Assists)

Isaiah Evans

Duke

(10.5)

J'Vonne Hadley

Louisville

(12.5) (6.5 Rebounds)

James Scott

Louisville

(7.5)

Khaman Maluach

Duke

(9.5) (6.5 Rebounds)

Kon Knueppel

Duke

(17.5)

Noah Waterman

Louisville

(6.5)

Sion James

Duke

(9.5)

Terrence Edwards

Louisville

(18.5)

Tyrese Proctor

Duke

(13.5)

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Odds to Win the 2025 NCAA Men's College Basketball Championship

Duke +350
Auburn +350
Florida +700
Houston +700
Alabama +1100
Tennessee +1600
Saint Johns +2200
Michigan State +2000
Iowa State +2500
Texas Tech +3000
Kentucky +4000
Maryland +4000
Texas A&M +5000
Arizona +5000
UConn +5000
Gonzaga +5000
Wisconsin +5000
BYU +5000
Kansas +5000
Missouri +6500
Clemson +6500
Purdue +8000
Illinois +8000
Oregon +10000
Ole Miss +10000
UCLA +10000
St. Mary's +10000
Michigan +10000
Memphis +10000
Louisville +10000
Creighton +10000
Arkansas +20000
Baylor +15000
Marquette +15000
Georgia +20000
Mississippi State +15000
Vanderbilt +15000
VCU +20000
Indiana +25000
UC San Diego +25000
Texas +30000
San Diego State +30000
Ohio State +30000
Oklahoma +30000
New Mexico +30000
Drake +30000
North Carolina +40000
Villanova +50000
Xavier +50000
Boise State +50000
SMU +50000
West Virginia +50000
Utah State +50000
George Mason +50000
Nebraska +50000
NC State +50000
Lipscomb +50000
Nebraska Omaha +50000
Nevada +50000
Grand Canyon +50000
Pittsburgh +50000
UC Irvine +50000
Dayton +50000
San Francisco +50000
Florida State +50000
Georgetown +50000
Kansas State +50000
Santa Clara +50000
SIU Edwardsville +50000
Winthrop +50000
North Alabama +50000
Bradley +50000
Cincinnati +50000
High Point +50000
McNeese +50000
North Texas +50000
Saint Louis +50000
Saint Josephs +50000

By Don Shapiro

Don is the lead sports reporter for Gambling911.com AM hours in North America and has been writing for the site for well over a decade. He was born and raised in New Jersey.