Bills vs. Broncos Point Spread – Fantasy Profile for Peyton Manning, Kyle Orton

Submitted by Mary Montgomery on

Written by :

Mary Montgomery

Published on :

The Bills vs. Broncos point spread had Denver as a -10 home favorite.  65% of the action was coming in on Denver here.  Claim Your FREE $250 Here (use bonus code G911).

Buffalo comes into this game with a surprising 7-5 record Straight Up while Denver is 9-3.  Both teams have paid out six times apiece to bettors.

Don’t expect this one to be a cakewalk for Denver.  The Bills have the best defensive efficiency in the NFL (4.5 expected points added per game), along with the most sacks (48) this season.  Buffalo’s defense leads the NFL in sacks (48) while posting the 2nd best opponent Total QBR (39.6). 

Peyton Manning is 7-4 in his career against the Bills. He has just 13 pass TD and 10 interceptions in 11 career games against the Bills.  With the Bills defense now allowing a passing touchdown in four of its past five games, fantasy owners beware when it comes to Manning this week.

The Bills are 10-25-1 Against The Spread in their last 36 games following a Straight Up win, 1-6 ATS in their last 7 road games vs. a team with a winning home record and are 2-10 ATS in their last 12 games after allowing less than 15 points in their previous game.

The Broncos have been red hot during the month of December, going 8-1 Against The Spread.

Denver is giving up the seventh-most fantasy points to opposing quarterbacks this season so we don’t recommend having the Bills starting QB in any fantasy lineup this week.

Fantasy aficionados should also be made aware that the Bills allow the second-fewest fantasy points to opposing running backs.

- Mary Montgomery, Gambling911.com

 

Related Content

Browns Trade Myles Garrett to Rams and Books Quick to React

Browns Trade Myles Garrett to Rams and Books Quick to React

Myles Garrett is heading to LA in exchange for two-time Pro Bowl pass rusher Jared Verse and multiple draft picks....and just like that, the Rams are Super Bowl favorites.
Green Bay Packers Josh Jacobs Arrested for Domestic Violence: Doesn't Bode Well for Packers 2026 Odds

Green Bay Packers Josh Jacobs Arrested for Domestic Violence: Doesn't Bode Well for Packers 2026 Odds

Green Bay Packers star running back Josh Jacobs was arrested Tuesday and booked on several domestic violence charges, according to the Hobart-Lawrence (Wisconsin) Police Department.
Bo Nix Broncos

Denver Broncos Spreads for All 2026 Regular Season Games

Remarkably, the Broncos still are listed as underdogs in seven games early on for the upcoming season, including five of the first six games. If they can start the season hot, we will have some idea where the Broncos are heading pretty quickly.
Aaron Rodgers Steelers

Bet on Will Aaron Rodgers be Benched By Steelers During 2026 Regular Season?

Aaron Rodgers announced earlier Wednesday that the upcoming season will be his last.