Alex Palou winning the 2025 Indy 500 pays out $500 for every $100 bet.

In 2024, Palou clinched his third NTT IndyCar Series title in four years.

And what a great start to the 2025 season with four wins in five races, including dominant performances at Barber Motorsports Park and the Sonsio Grand Prix at Indianapolis, where he led 81 of 90 laps.

The 28-year-old comes into this race more confident than ever.

"I got to experience different parts of the 500, like running up front, running in the back, having to overtake, having a fast car, having not such a fast car.

“I feel more ready than ever, and I think it’s enough to win, so that’s why. And I’m hungry to win it.

2025 Indy 500 Odds

*All Odds Courtesy of BetUS

Rot     Odds to Win IndyCar Series Indianapolis 500     Moneyline
1001     Alex Palou         +500
1002     Pato O`Ward         +500
1003     Scott Dixon         +650
1004     Josef Newgarden         +800
1005     Scott McLaughlin         +850
1006     Robert Shwartzman         +900
1007     Felix Rosenqvist         +1400
1008     Takuma Sato         +900
1009     Kyle Larson         +1600
1010     Will Power         +1900
1011     Colton Herta         +2500
1012     David Malukas         +2200
1013     Alexander Rossi         +2200
1014     Christian Lundgaard         +2200
1015     Marcus Ericsson         +2500
1016     Santino Ferrucci         +3000
1017     Kyle Kirkwood         +3000
1018     Helio Castroneves         +2700
1019     Conor Daly         +3500
1020     Ed Carpenter         +6000
1021     Rinus Veekay         +8000
1022     Graham Rahal         +8000
1023     Marcus Armstrong         +8000
1024     Ryan Hunter-Reay         +8000
1025     Louis Foster         +8000
1026     Nolan Siegel         +10000
1027     Christian Rasmussen         +10000
1028     Sting Ray Robb         +10000
1029     Marco Andretti         +12500
1030     Callum Ilott         +12500
1031     Kyffin Simpson         +12500
1032     Jack Harvey         +15000
1033     Devlin Defrancesco         +20000
Driver must start.

IndyCar Series Indianapolis 500 : Podium Finish
Sun, May 25, 2025 EST
Rot     Podium Finish IndyCar Series Indianapolis 500     Moneyline
1101     Alex Palou         +160
1102     Pato O`Ward         +130
1103     Scott Dixon         +200
1104     Josef Newgarden         +240
1105     Scott McLaughlin         +260
1106     Robert Shwartzman         +260
1107     Felix Rosenqvist         +350
1108     Takuma Sato         +260
1109     Kyle Larson         +475
1110     Will Power         +550
1111     Colton Herta         +750
1112     David Malukas         +550
1113     Alexander Rossi         +600
1114     Christian Lundgaard         +600
1115     Marcus Ericsson         +750
1116     Santino Ferrucci         +850
1117     Kyle Kirkwood         +850
1118     Helio Castroneves         +850
1119     Conor Daly         +1000
1120     Ed Carpenter         +1600
1121     Rinus Veekay         +2000
1122     Graham Rahal         +2000
1123     Marcus Armstrong         +2000
1124     Ryan Hunter-Reay         +2000
1125     Louis Foster         +2000
1126     Nolan Siegel         +2200
1127     Christian Rasmussen         +2200
1128     Sting Ray Robb         +2200
1129     Marco Andretti         +2800
1130     Callum Ilott         +2800
1131     Kyffin Simpson         +2800
1132     Jack Harvey         +3500
1133     Devlin Defrancesco         +4000
Driver must start.

IndyCar Series Indianapolis 500 : Top 5 Finish
Sun, May 25, 2025 EST
Rot     Top 5 Finish IndyCar Series Indianapolis 500     Moneyline
1201     Pato O`Ward         -105
1202     Alex Palou         -105
1203     Scott Dixon         +130
1204     Josef Newgarden         +160
1205     Scott McLaughlin         +160
1206     Takuma Sato         +160
1207     Robert Shwartzman         +200
1208     Felix Rosenqvist         +240
1209     Kyle Larson         +275
1210     Alexander Rossi         +360
1211     David Malukas         +360
1212     Christian Lundgaard         +360
1213     Will Power         +400
1214     Colton Herta         +400
1215     Marcus Ericsson         +400
1216     Helio Castroneves         +450
1217     Kyle Kirkwood         +450
1218     Santino Ferrucci         +450
1219     Conor Daly         +500
1220     Ed Carpenter9         +900
1221     Graham Rahal         +1000
1222     Ryan HunterReay         +1000
1223     Marcus Armstrong         +1000
1224     Louis Foster         +1000
1225     Rinus Veekay         +1200
1226     Marco Andretti         +1200
1227     Christian Rasmussen         +1400
1228     Sting Ray Robb         +1200
1229     Nolan Siegel         +1200
1230     Callum Ilott         +1400
1231     Kyffin Simpson         +1400
1232     Jack Harvey         +1500
1233     Devlin Defrancesco         +1500
Driver must start.

IndyCar Series Indianapolis 500 : Winning Manufacturer
Sun, May 25, 2025 EST
Rot     Winning Manufacturer IndyCar Series Indianapolis 500     Moneyline
1301     Chevrolet         -130
1302     Honda         Ev
All wagers have action.

IndyCar Series Indianapolis 500 : Winning Car Number
Sun, May 25, 2025 EST
Rot     Winning Car Number IndyCar Series Indianapolis 500     Moneyline
1401     Over  9½       -135
1402     Under  9½       +105
All wagers have action.

IndyCar Series Indianapolis 500 : Group Betting
Sun, May 25, 2025 EST
Rot     Odds To Win Group A IndyCar Series Indianapolis 500     Moneyline
1501     Alex Palou         +230
1502     Pato O`Ward         +250
1503     Scott Dixon         +250
1504     Josef Newgarden         +325
All drivers must start.

Rot     Odds To Win Group B IndyCar Series Indianapolis 500     Moneyline
1505     Scott McLaughlin         +250
1506     Robert Shwartzman         +260
1507     Takuma Sato         +260
1508     Felix Rosenqvist         +270
All drivers must start.

Rot     Odds To Win Group C IndyCar Series Indianapolis 500     Moneyline
1509     Will Power         +250
1510     Christian Lundgaard         +260
1511     Alexander Rossi         +260
1512     Colton Herta         +260