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There are four games in Week 16 that pit likely playoff teams including four divisional favorites. Denver/LAC, Houston/KC, Pittsburgh/Baltimore and Minnesota/Seattle.
Every Friday, BetOnline.ag releases look-ahead lines for the following week. The look-ahead numbers are taken down on Sunday right before the games start, and then they are re-opened Sunday evening.
If there’s significant movement (1.5 points or more) from the look-ahead spread or total that are released prior to Week 15, that will be notated under the opening line below.
NFL Week 16 spreads are subject to change. Here are the odds in real time.
NFL Week 16 Opening Odds
Thursday, Dec 19, 2024
- Denver @ Los Angeles Chargers (-3, 42)
Saturday, December 21, 2024
- Houston (-3, 41.5) @ Kansas City
- Line opened KC -3. Mahomes injury moved it 6.5 points. Total opened at 44.
- Pittsburgh @ Baltimore (-7, 46.5)
- Line opened Baltimore -5.
Sunday, Dec 22, 2024
- Cleveland @ Cincinnati (-7, 49.5)
- Detroit (-7, 47) @ Chicago
- Arizona (-4, 46) @ Carolina
- New England @ Buffalo (-14, 44.5)
- Total opened at 46.5.
- Philadelphia (-4 46.5) @ Washington
- New York Giants @ Atlanta (-9.5, 42)
- Tennessee @ Indianapolis (-4.5, 42,5)
- San Francisco @ Miami (-2.5, 46.5)
- Total opened at 49.
- Los Angeles Rams (-3, 46.5) @ New York Jets
- Minnesota (-2, 45.5) @ Seattle
- Jacksonville @ Las Vegas (-1, 39.5)
- Tampa Bay (-3.5, 47.5) @ Dallas
Monday, Dec 23, 2024
- New Orleans @ Green Bay (-13.5, 43)
