49ers vs. Buccaneers Betting Preview November 10

The 4-4 49ers take on the 4-5 Buccaneers in Tampa Sunday.

49ers @ Bucs

Opening Line - The line opened as low as 49ers -5.5 at DraftKings.

Line Trend  - This one has moved from -5.5 to -6.5.

Sagarin – Sagarin gives us a number of 49ers 3.57, indicative of an overlay.

Action Trend – 85% of the action was on the 49ers.

Comparables

• Cincinnati -4.5 to -6.5 New York Jets (road favorite Cincinnati covers with 15 point win) Cincinnati 7.01 2.5 overlay to On the Money - Road favorite covers.
• Philadelphia -4.5 to -6.5 Washington (road favorite Philadelphia covers and wins by a lot) Philadelphia 5.1 - On the Money to 1.5 Overlay.  Road favorite covers.

49ers Player to Watch

TE George Kittle is coming off a six-catch, 128-yard performance before the bye and has been the team’s most dependable pass catcher this season. Kittle has 500 catches and needs eight this week to tie Roger Craig for the third most in franchise history. He already ranks third with 6,777 yards receiving.

Bucs Player to Watch

TE Cade Otton has emerged as Baker Mayfield’s go-to option in the absence of injured WRs Mike Evans and Chris Godwin. He has 25 receptions for 258 yards and three TDs over the past three weeks. During that stretch, Travis Kelce (28) is the only tight end with more catches. Otton has at least eight receptions each of the past three games and can become the first tight end since Kelce in 2020 to have eight-plus catches and 75-plus receiving yards in four consecutive games.

Key Matchup

San Francisco’s balanced offense against a Tampa Bay defense that’s struggled to stop opponents on third down and ranks 19th against run, 30th against the pass and 28th in points allowed.

Key Injuries

RB Christian McCaffrey (Achilles tendon) returned to practice on Monday and could make his season debut if he has no setbacks during the week. ... WR Jauan Jennings (hip and K Jake Moody (ankle) also could return for San Francisco after missing time before the bye week. … WR Mike Evans (hamstring) is expected to miss his third straight game. The Bucs remain hopeful that he will be ready to return after next week’s bye. … NT Greg Gaines (calf) also sat out the past two games. His status for Sunday will be monitored as the week progresses.