NFL Week 15 Betting Lines - 2025

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Indianapolis’ dream year turned into a nightmare when Daniel Jones’ non-contact injury may have signaled the end of the Colts’ season.

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Indianapolis’ dream year turned into a nightmare when Daniel Jones’ non-contact injury may have signaled the end of the Colts’ season.

Oh, and the Giants had a great bye week due to the Titans win, which gives the New York Football Giants the pole position for the first overall pick in the draft.

On to Week 15, which has a nice slate of games, highlighted by Buffalo at New England, Detroit at Rams, Indy at Seattle and Green Bay at Denver.

If there’s a spread movement of one point or more compared to the lookahead lines that were released earlier this week, we’ve noted it underneath the current spread.

There was more line movement from the lookahead lines than any other week this season.

NFL Week 15 spreads are subject to change. Here’s the direct link to those odds: https://www.betonline.ag/sportsbook/football/nfl.

NFL Week 15 Lines

 

Thursday, December 10, 2025

 

Atlanta Falcons at Tampa Bay Buccaneers (-5½)

 

Sunday, December 14, 2025

 

Cleveland Browns at Chicago Bears (-7)

 

Baltimore Ravens at Cincinnati Bengals (+2½)

 

Los Angeles Chargers at Kansas City Chiefs (-4½)

 

Buffalo Bills at New England Patriots (+1½) Note: Lookahead line opened Patriots -1½. We have a new favorite in this game.

 

Washington Commanders at New York Giants (-1½) Note: Lookahead line opened Giants +2½. We have a new favorite.

 

Las Vegas Raiders at Philadelphia Eagles (-13)

 

New York Jets at Jacksonville Jaguars (-11½) Note: Lookahead line opened Jaguars -9½.

 

Arizona Cardinals at Houston Texans (-7½)

 

Green Bay Packers at Denver Broncos (+1½) Note: Lookahead line opened as a pick’em.

 

Detroit Lions at Los Angeles Rams (-4½)

 

Carolina Panthers at New Orleans Saints (+3)

 

Tennessee Titans at San Francisco 49ers (-12½)

 

Indianapolis Colts at Seattle Seahawks (-10) Note: Lookahead line opened Colts -3½. Injury to Jones moved this game 6½ points.

 

Minnesota Vikings at Dallas Cowboys (-6) Note: Lookahead line opened Cowboys -7

           

Monday, December 15, 2025

 

Miami Dolphins at Pittsburgh Steelers (-3½)

-BetOnline Press 

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