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49ers are a -1 point favorite in this game
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This one will be played in a neutral location in Arizona
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Buffalo and San Francisco haven't gone head-to-head since 2016
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The Buffalo Bills vs. San Francisco 49ers line Monday night was set at 49ers -1.
Action was pretty balanced on the spread but 80% on the moneyline for the Bills.
This is a rare neutral game being played at State Farm Stadium in Glendale, Ariz due to California Covid-19 restrictions.
San Francisco looks to reach the .500 mark and compete in the NFC West while Buffalo is hoping to hold off the Miami Dolphins.
Buffalo and San Francisco haven't gone head-to-head since 2016 and haven't met in a closely contested game since a 10-3 49ers road win in 2008.
The scores of the two meetings since have been 45-3 (49ers) and 45-16 (Bills), with the home team winning each.
Prop Bets
Rot |
Josh Allen (BUF) Total Completions |
Moneyline |
701 |
Over 23½ Completions |
|
702 |
Under 23½ Completions |
|
Rot |
Josh Allen (BUF) Total Passing Yards |
Moneyline |
703 |
Over 269½ Passing Yards |
|
704 |
Under 269½ Passing Yards |
|
Rot |
Josh Allen (BUF) Total Touchdown Passes |
Moneyline |
705 |
Over 1½ Touchdown Passes |
|
706 |
Under 1½ Touchdown Passes |
|
Rot |
Josh Allen (BUF) Will He Throw an Interception |
Moneyline |
707 |
Yes |
|
708 |
No |
|
Rot |
Josh Allen (BUF) Longest Completion |
Moneyline |
709 |
Over 37½ Longest Completion |
|
710 |
Under 37½ Longest Completion |
|
Rot |
Josh Allen (BUF) Total Rushing Yards |
Moneyline |
711 |
Over 31½ Rushing Yards |
|
712 |
Under 31½ Rushing Yards |
|
Rot |
Devin Singletary (BUF) Total Rushing Yards |
Moneyline |
713 |
Over 38½ Rushing Yards |
|
714 |
Under 38½ Rushing Yards |
|
Rot |
Zack Moss (BUF) Total Rushing Yards |
Moneyline |
715 |
Over 37½ Rushing Yards |
|
716 |
Under 37½ Rushing Yards |
|
Rot |
Stefon Diggs (BUF) Total Receptions |
Moneyline |
717 |
Over 6½ Receptions |
|
718 |
Under 6½ Receptions |
|
Rot |
Stefon Diggs (BUF) Total Receiving Yards |
Moneyline |
719 |
Over 80½ Receiving Yards |
|
720 |
Under 80½ Receiving Yards |
|
Rot |
Stefon Diggs (BUF) Longest Reception |
Moneyline |
721 |
Over 24½ Longest Reception |
|
722 |
Under 24½ Longest Reception |
|
Rot |
Cole Beasley (BUF) Total Receptions |
Moneyline |
723 |
Over 4½ Receptions |
|
724 |
Under 4½ Receptions |
|
Rot |
Cole Beasley (BUF) Total Receiving Yards |
Moneyline |
725 |
Over 56½ Receiving Yards |
|
726 |
Under 56½ Receiving Yards |
|
Rot |
Cole Beasley (BUF) Longest Reception |
Moneyline |
727 |
Over 21½ Longest Reception |
|
728 |
Under 21½ Longest Reception |
|
Rot |
Tyler Bass (BUF) Total Points |
Moneyline |
729 |
Over 6½ Points |
|
730 |
Under 6½ Points |
|
Rot |
Nick Mullens (SF) Total Completions |
Moneyline |
801 |
Over 22½ Completions |
|
802 |
Under 22½ Completions |
|
Rot |
Nick Mullens (SF) Total Passing Yards |
Moneyline |
803 |
Over 252½ Passing Yards |
|
804 |
Under 252½ Passing Yards |
|
Rot |
Nick Mullens (SF) Total Touchdown Passes |
Moneyline |
805 |
Over 1½ Touchdown Passes |
|
806 |
Under 1½ Touchdown Passes |
|
Rot |
Nick Mullens (SF) Will He Throw an Interception |
Moneyline |
807 |
Yes |
|
808 |
No |
|
Rot |
Nick Mullens (SF) Longest Completion |
Moneyline |
809 |
Over 36½ Longest Completion |
|
810 |
Under 36½ Longest Completion |
|
Rot |
Raheem Mostert (SF) Total Rushing Yards |
Moneyline |
811 |
Over 59½ Rushing Yards |
|
812 |
Under 59½ Rushing Yards |
|
Rot |
First To Score |
Moneyline |
1001 |
Bills |
|
1002 |
49ers |
|
Rot |
Score in 1st 6 min |
Moneyline |
1003 |
Yes |
|
1004 |
No |
|
Rot |
First Score of the Game |
Moneyline |
1005 |
TD |
|
1006 |
Any Other Score |
|
Rot |
First Scoring Play |
Moneyline |
1007 |
Bills TD |
|
1008 |
Bills FG |
|
1009 |
Bills Any Other Score |
|
1010 |
49ers TD |
|
1011 |
49ers FG |
|
1012 |
49ers Any Other Score |
|
Rot |
Will there be a Defensive or Special Teams TD |
Moneyline |
1013 |
Yes |
|
1014 |
No |
|
Rot |
Total TDs in the Game |
Moneyline |
1015 |
Over 5½ TDs |
|
1016 |
Under 5½ TDs |
|
Rot |
Total FGs Scored in the Game |
Moneyline |
1017 |
Over 2½ FGs |
|
1018 |
Under 2½ FGs |
|
Rot |
Longest TD in the Game |
Moneyline |
1019 |
Over 40½ Yards |
|
1020 |
Under 40½ Yards |
|
Rot |
Shortest TD in the Game |
Moneyline |
1021 |
Over 1½ Yards |
|
1022 |
Under 1½ Yards |
|
Rot |
Longest FG Scored in the Game |
Moneyline |
1023 |
Over 45½ Yards |
|
1024 |
Under 45½ Yards |
|
Rot |
A Team to Score 3 Unanswered Times |
Moneyline |
1025 |
Yes |
|
1026 |
No |
|
Rot |
Team To Score Longest TD |
Moneyline |
1027 |
Bills |
|
1028 |
49ers |
|
Rot |
Team To Score Longest FG |
Moneyline |
1029 |
Bills |
|
1030 |
49ers |
|
Rot |
Team Scoring 1st Wins Game |
Moneyline |
1031 |
Yes |
|
1032 |
No |
|
Rot |
Team to Call 1st Timeout |
Moneyline |
1033 |
Bills |
|
1034 |
49ers |
|
Rot |
Double Result |
Moneyline |
1035 |
Bills/Bills |
|
1036 |
Bills/Tie |
|
1037 |
Bills/49ers |
|
1038 |
Tie/Bills |
|
1039 |
Tie/Tie |
|
1040 |
Tie/49ers |
|
1041 |
49ers/Bills |
|
1042 |
49ers/Tie |
|
1043 |
49ers/49ers |
|
Rot |
Race To 10 Points |
Moneyline |
1044 |
Bills |
|
1045 |
49ers |
|
1046 |
Neither |
|
Rot |
Will the Game go to Overtime |
Moneyline |
1047 |
Yes |
|
1048 |
No |
|
Rot |
Highest Scoring Half |
Moneyline |
1049 |
1st Half |
|
1050 |
2nd Half |
|
1051 |
Tie |
|
Rot |
Highest Scoring Quarter |
Moneyline |
1052 |
1st Quarter |
|
1053 |
2nd Quarter |
|
1054 |
3rd Quarter |
|
1055 |
4th Quarter |
|
1056 |
Tie |
|
Rot |
Winning Margin |
Moneyline |
1057 |
Bills to win by 1-3 pts |
|
1058 |
Bills to win by 4-6 pts |
|
1059 |
Bills to win by 7-10 pts |
|
1060 |
Bills to win by 11-13 pts |
|
1061 |
Bills to win by 14-17 pts |
|
1062 |
Bills to win by 18-21 pts |
|
1063 |
Bills to win by 22 or more pts |
|
1064 |
49ers to win by 1-3 pts |
|
1065 |
49ers to win by 4-6 pts |
|
1066 |
49ers to win by 7-10 pts |
|
1067 |
49ers to win by 11-13 pts |
|
1068 |
49ers to win by 14-17 pts |
|
1069 |
49ers to win by 18-21 pts |
|
1070 |
49ers to win by 22 or more pts |
|
Rot |
Total Points Scored |
Moneyline |
1071 |
00-14 Points |
|
1072 |
15-21 Points |
|
1073 |
22-28 Points |
|
1074 |
29-35 Points |
|
1075 |
36-42 Points |
|
1076 |
43-49 Points |
|
1077 |
50-56 Points |
|
1078 |
57-63 Points |
|
1079 |
64-70 Points |
|
1080 |
71-77 Points |
|
1081 |
78 or More Points |
|
Rot |
1st Half Total TDs Scored |
Moneyline |
1082 |
Over 2½ TDs |
|
1083 |
Under 2½ TDs |
|
Rot |
1st Half Total FGs Scored |
Moneyline |
1084 |
Over 1½ FGs |
|
1085 |
Under 1½ FGs |
|
Rot |
Score in Last 2 min of the 1st Half |
Moneyline |
1086 |
Yes |
|
1087 |
No |
|
- Mary Montgomery, Gambling911.com