2025 Final Four Betting Odds Now Up - Chalkiest of the Chalk

For the first time since 2008, all four No. 1 seeds have made the Final Four.


The oddsmakers at BetOnline.ag set the odds of all four top seeds making the Final Four at 10/1 pre-tourney, and it was bet so much that it closed at 5/1.

That same prop for the 2024 Men’s Tournament was 33/1.

So, while it’s still surprising to see all four 1 seeds in the Final Four, the oddsmakers understood it had a good chance this year.

Additionally, the last 14 favorites against-the-spread (ATS) during the madness have all won the games outright. The last favorite to lose a game in this tournament was Iowa State to Ole Miss.

Below are the current Final Four game lines and odds to win the tournament.

Final Four Game Lines:    
 
Houston vs Duke (-4.5, 137)

Note: This line and total has held steady from the initial line.

 Florida (-3, 161.5) vs Auburn

Note: This line opened Florida -2.5 with a total of 162.5.

NCAA Tournament Champion

#1 Duke
   
11/10
   
(+110)

#1 Florida   

13/5
   
(+260)

#1 Houston
   
4/1

(+400)

#1 Auburn
   
5/1

(+500)