2025 NFL Week 1 Spreads and Totals Now Available

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NFL games have been trickling out since Monday, and now we have the full Week 1 schedule.

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The guys at BetOnline.ag are the first to publish spreads for all 16 games of Week 1.

NFL Week 1 Lines

Thursday September 4

  • Dallas Cowboys at Philadelphia Eagles (-7, 47)

Friday September 5

  • Kansas City Chiefs at Los Angeles Chargers (+2.5, 44)

Note: Technically the Chargers are the home team, but the game is at a neutral site in Brazil.

Sunday September 7

  • Miami Dolphins at Indianapolis Colts (-1.5)
  • Las Vegas Raiders at New England Patriots (-2.5)
  • Pittsburgh Steelers at New York Jets (N/A due to Rodgers/QB situation)
  • Cincinnati Bengals at Cleveland Browns (+5)
  • Carolina Panthers at Jacksonville Jaguars (-2.5)
  • New York Giants at Washington Commanders (-7)
  • Tampa Bay Buccaneers at Atlanta Falcons (pick 'em)
  • Arizona Cardinals at New Orleans Saints (+2)
  • Detroit Lions at Green Bay Packers (pick 'em)
  • Tennessee Titans at Denver Broncos (-6.5)
  • Houston Texans at Los Angeles Rams (-2.5)
  • San Francisco 49ers at Seattle Seahawks (+2.5)
  • Baltimore Ravens at Buffalo Bills (-1, 53.5)

Monday September 8

  • Minnesota Vikings at Chicago Bears (pick 'em, 44.5)

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